Inhibition of choline metabolism in an angioimmunoblastic T-cell lymphoma preclinical model reveals a new metabolic vulnerability as possible target for treatment.

Auteurs Krug A, Tosolini M, Madji Hounoum B, Fournié JJ, Geiger R, Pecoraro M, Emond P, Gaulard P, Lemonnier F, Ricci JE, Verhoeyen E

Journal of experimental & clinical cancer research : CR Feb 2024

Roles of innate lymphoid cells in metabolic and alcohol-associated liver diseases.

Auteurs Bourinet M, Anty R, Gual P, Luci C

JHEP reports : innovation in hepatology Feb 2024

Targeting cancer and immune cell metabolism with the complex I inhibitors metformin and IACS-010759.

Auteurs Pujalte-Martin M, Belaïd A, Bost S, Kahi M, Peraldi P, Rouleau M, Mazure NM, Bost F

Molecular oncology Jan 2024

Design, Synthesis and Biological Evaluation of Novel Anticancer Amidinourea Analogues via Unexpected 1,3,5-Triazin-2-one Ring Opening.

Auteurs Grytsai O, Hamouda-Tekaya N, Botton T, Rocchi S, Benhida R, Ronco C

ChemMedChem Dec 2023

Impact of rising seawater temperature on a phagocytic cell population during infection in the sea anemone .

Auteurs Billaud M, Larbret F, Czerucka D

Frontiers in immunology Dec 2023

The mitochondrial NADH shuttle system is a targetable vulnerability for Group 3 medulloblastoma in a hypoxic microenvironment.

Auteurs Contenti J, Guo Y, Mazzu A, Irondelle M, Rouleau M, Lago C, Leva G, Tiberi L, Ben-Sahra I, Bost F, Mazure NM

Cell death & disease Nov 2023

An exploratory human study investigating the influence of type 2 diabetes on macrophage phenotype after myocardial infarction.

Auteurs Moratal C, Murdaca J, Cruzel C, Zamiti-Smondel A, Heme N, Asarisi F, Neels JG, Ferrari E, Chinetti G

International journal of cardiology. Heart & vasculature Nov 2023

LKB1-SIK2 loss drives uveal melanoma proliferation and hypersensitivity to SLC8A1 and ROS inhibition.

Auteurs Proteau S, Krossa I, Husser C, Guéguinou M, Sella F, Bille K, Irondelle M, Dalmasso M, Barouillet T, Cheli Y, Pisibon C, Arrighi N, Nahon-Estève S, Martel A, Gastaud L, Lassalle S, Mignen O, Brest P, Mazure NM, Bost F, Baillif S, Landreville S, Turcotte S, Hasson D, Carcamo S, Vandier C, Bernstein E, Yvan-Charvet L, Levesque MP, Ballotti R, Bertolotto C, Strub T

EMBO molecular medicine Nov 2023

Adipocyte glucocorticoid receptor activation with high glucocorticoid doses impairs healthy adipose tissue expansion by repressing angiogenesis.

Auteurs Vali A, Dalle H, Loubaresse A, Gilleron J, Havis E, Garcia M, Beaupère C, Denis C, Roblot N, Poussin K, Ledent T, Bouillet B, Cormont M, Tanti JF, Capeau J, Vatier C, Fève B, Grosfeld A, Moldes M

Diabetes Nov 2023

Super-enhancer-driven expression of BAHCC1 promotes melanoma cell proliferation and genome stability.

Auteurs Berico P, Nogaret M, Cigrang M, Lallement A, Vand-Rajabpour F, Flores-Yanke A, Gambi G, Davidson G, Seno L, Obid J, Vokshi BH, Le Gras S, Mengus G, Ye T, Cordero CF, Dalmasso M, Compe E, Bertolotto C, Hernando E, Davidson I, Coin F

Cell reports Nov 2023